Sitagliptin: MedlinePlus Drug Information

If you’re interested in finding an alternative to Januvia, talk with your doctor. They can tell you about other medications that may work well for you. The Food and Drug Administration (FDA) approves prescription drugs such as Januvia to treat certain conditions.

Why is this medication prescribed?

1. Different medical groups recommend different A1C levels, so it’s always best to ask your doctor what’s best for you.
2. They may also recommend a dietitian to help make sure you get the proper nutrition.
3. There have been postmarketing reports of acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis, in patients taking JANUVIA.
4. Six metabolites were detected at trace levels and are not expected to contribute to the plasma DPP-4 inhibitory activity of sitagliptin.
5. Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems.
6. It doesn’t matter if you take the drug with or without food.

How often you’ll need to check depends on several factors. These include other diabetes drugs you’re taking and whether you’ve had low blood sugar levels in the past. Januvia (sitagliptin) is an oral types 2 diabetes medicine that can help you lower your blood sugar and reach your target goals. It typically does not cause low blood sugar or weight gain when used alone without other diabetes medications.

Is weight gain a side effect of JANUVIA?

They obtained their data by administering sitagliptin and metformin. They found using both drugs lowered A1C and FPG more than using either drug alone. About 5,200 people participated in cocaine detection the initial clinical trials for Januvia. The majority of study participants were white and the average age was 55 years. Both Januvia and Janumet reduced blood sugar in clinical trials.

JANUVIA may help lower your blood sugar (A1C).

To learn more about saving money on prescriptions, check out this article. For additional information about the cost of Januvia, see this article. As with all medications, the cost of Januvia can vary. The actual price you’ll pay depends on your insurance plan if you have one, your location, and the pharmacy you use. If you realize that you’ve missed a dose of Januvia, take it as soon as you can.

Could I be prescribed a daily dose of 200 mg of Januvia?

Like Januvia, metformin is also used to treat high blood sugar caused by type 2 diabetes. Here we look at how Januvia and metformin are alike and different. However, a study in Taiwan found that people who took Januvia had a higher chance of developing thyroid cancer. This was compared to people who had diabetes but didn’t take Januvia. Yet no clinical studies in the United States have linked Januvia to thyroid cancer.

Januvia for type 2 diabetes

If you have symptoms of pancreatitis while you’re taking Januvia, seek emergency medical care right away. Low blood sugar may occur more frequently if you take Januvia with certain other medications, such as insulin or sulfonylureas. A1C is a simple blood test that shows the average https://sober-home.org/bath-salts-drug-effects-abuse-health-warnings/ amount of sugar (glucose) in your blood over the past 2 to 3 months, letting you know how well your blood sugar is being controlled over time. It is often used to diagnose as well as monitor type 2 diabetes. A1C is also called HbA1c or the glycated hemoglobin A1C test.

Do not drink alcohol while taking Januvia without talking to your doctor first. While you’re taking Januvia, your doctor will monitor your blood sugar and hemoglobin A1c levels to see how well the medication is working. Hemoglobin A1c (HbA1c) is hemoglobin (a protein in red blood cells) that’s attached to sugar. A test for HbA1c measures what your average blood sugar level was over the past 2–3 months. Some people can take Januvia alone or with other oral drugs to treat type 2 diabetes.

If you need help remembering to take your dose of Januvia on time, try using a medication reminder. This can include setting an alarm, downloading a reminder app, or setting a 100 most inspiring addiction recovery quotes timer on your phone. However, your doctor may prescribe a lower dosage of Januvia if you have a kidney problem. In this case, your dosage may be 25 mg or 50 mg once per day.

Rescue glycemic therapy was used in 5% of patients treated with JANUVIA 100 mg and 14% of patients treated with placebo. A similar decrease in body weight was observed for both treatment groups. In a randomized, placebo-controlled crossover study, 79 healthy subjects were administered a single oral dose of sitagliptin 100 mg, sitagliptin 800 mg (8 times the recommended dose), and placebo.

Tell your healthcare provider right away if you have any of the following symptoms of heart failure. Tell your healthcare provider right away if you have new or increased joint pain while taking this medicine. Januvia is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Keep people safe from potentially harmful drugs, medical devices and procedures by informing them of medical conditions, severe side effects and ways to take action. Because the kidneys filter Januvia out of the body, people whose kidneys are not fully functioning may need a lower dose of Januvia. The recommended dose for people with moderate kidney impairment is 50 mg and 25 mg for patients with severe kidney impairment or end-stage kidney disease that requires dialysis.

Sitagliptin is a P-gp substrate, but does not inhibit P-gp mediated transport of digoxin. Based on these results, sitagliptin is considered unlikely to cause interactions with other drugs that utilize these pathways. Sitagliptin administered to female rats from gestation day 6 to lactation day 21 caused no functional or behavioral toxicity in offspring of rats at doses up to 1000 mg/kg.